Orientation-averaged optical properties of spheroid dust aerosol particles are carried out based on discrete dipole approximation for size parameters from 0.1 to 23 (corresponding to effective radius from 0.01 to 2 μm at wavelength of 550 nm). The effects of the asphericity degree on aerosol optical properties and whether properties of orientation-averaged nonspherical particles can be replaced by those of effective isovolumetric spherical particles are also studied. For monodisperse and polydisperse spheroid dust, distinctive asphericity can generally induce distinctive deviations from their effective isovolumetric spherical particles for extinction efficiency factor, asymmetry parameter and single scattering albedo. For the same asphericity, the deviations of asymmetry parameter of nonspherical particles from their isovolumetric spheres are larger than those of extinction efficiency factor and single scattering albedo. Optical properties of orientation-averaged nonspherical particles cannot be rigorously replaced by those of their effective isovolumetric spheres. Orientation-averaged extinction efficiency factors, asymmetry parameters and single scattering albedos of nonspherical aerosols can be approximately replaced by those of their effective isovolumetric spheres, if the asphericity is small. However, for large asphericity, the approximate replacement happens only for the single scattering albedo with its deviation within 3% for spheroid dust at aspect ratio of 16 as an example.