本文以纳米金为模板，通过替代化学反应，合成 Au@AgNPs 核壳纳米粒子，将其负载在聚(苯乙烯-丁二烯) (SB)电纺纤维膜上，制得表面增强拉曼散射(SERS) 柔性基底Au@AgNPs/SB。利用紫外-可见光谱 (UV-vis)、透射电子显微镜 (TEM)、扫描电子显微镜 (SEM)和拉曼光谱表征了基底的形貌结构和光谱性能。以罗丹明6G为拉曼分子探针，将Au@AgNPs/SB基底经常温-升温过程处理后进行光谱实验，结果表明该基底有热耐受性好，能用于较高温度下前处理样品，有利于提高检测的灵敏度。以农药福美双作为研究对象，通过对其进行加热实验，SERS检测限可低至3.65×10-9mol/L。

In this paper, Au@AgNPs core-shell nanoparticles are synthesized by using nano-Au seeds template method and then loaded on the poly (styrene butadiene) (SB) fiber membrane made-by electrospinning to prepare Au@AgNPs /SB as the surface enhanced Raman scattering (SERS) flexible substrate. Ultraviolet-visible spectroscopy (UV-vis), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and Raman spectroscopy are used to characterize the morphology and spectral properties of such substrate. Using Rhodamine 6G as a Raman molecular probe, on Au@AgNPs, SERS spectra are recorded after temperature-rise process, showing good thermal tolerance of Au@AgNPs /SB substrate. Therefore, Au@AgNPs /SB substrate could be utilized to detect the target samples pretreated samples at relatively high temperatures, and is conducive to improving the detection sensitivity. Taking the SERS detection of thiram as proof of concept, the limit of detection can be as low as 3.65×10-9 mol/L by using Au@AgNPs /SB extraction of thiram in a hot solution.