由于光纤长度可控以及其独特的光学性能使得光纤SERS基底的检测灵活简单，在本研究中，采用油水分离的实验方法在光纤端面上修饰了银纳米颗粒，证明了该方法可以制备光纤SERS基底并有效增强拉曼信号。我们将结晶紫溶液作为分析物对制备的SERS光纤基底进行了表征，并对光纤SERS基底的均匀性、灵敏度和稳定性三个方面进行了研究。在实际应用中，使用光纤基底对罗丹明6G和农药中间体合成中广泛使用的4-氨基苯硫酚进行了检测。这些实验结果证明了自组装法为光纤SERS基底的制备提供了可行思路。

Due to the controllable length of the fiber and its unique optical performance, the detection of the fiber SERS substrate is flexible and simple. In this study, silver nanoparticles were modified on the fiber end face using an oil-water separation experimental method, proving that this method can prepare the fiber SERS substrate and effectively enhance Raman signals. We used Crystal violet solution as the analyte to characterize the SERS fiber matrix, and studied the uniformity, sensitivity and stability of the fiber SERS substrate. In practical application, optical fiber substrate was used to detect 4-aminonenenebb thiophenol, which is widely used in the synthesis of Rhodamine 6G and pesticide intermediates. These experimental results demonstrate that the self-assembly method provides a feasible approach for the preparation of fiber SERS substrates.