本文通过对尿液进行前处理，实现了人体尿液中毒品快速分离和纯化。并且，我们以自组装的金纳米棒为SERS基底对纯化的尿样进行检测，结合便携式拉曼光谱仪成功实现了对尿液中冰毒、摇头丸、甲卡西酮的分析检测，具有很高的灵敏性。整个纯化和检测过程只需要~3.5 min，该方法方便、快捷，有望实现现场对吸毒人员尿样中毒品的灵敏性检测。

The drugs was rapidly separated and purified in human urine sample by pretreatment. Furthermore, the self-assembled gold nanorods were used as the substrate to detect the drugs in real purifiedhuman urine byportable Raman spectrometer. It was found that our substratepresent excellent sensitivity of methamphetamine (MAMP), 3,4-methylenedioxy-methamphetamine (MDMA) and methcathinone(MCAT) detection.The whole process of the purifiedand detected procedurecan be completed in ~3.5 min.Therefore, our platform for detecting drugs promises a great prospective towards a rapid, reliable and on-spot detection method.