SERS detection methods for several key molecules in the oxidative stress process of cells

YUE Jing, SHEN Yanting, WANG Jiaqi, XU Weiqing, XU Shuping

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Chinese Journal of Light Scattering ›› 2019, Vol. 31 ›› Issue (4) : 317-325. DOI: 10.13883/j.issn1004-5929.201904003
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SERS detection methods for several key molecules in the oxidative stress process of cells

  • YUE Jing, SHEN Yanting, WANG Jiaqi, XU Weiqing, XU Shuping*
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Abstract

Oxidative stress is associated with the development of various diseases including cancer, cardiovascular disease, neurodegenerative diseases and diabetes mellitus. In response to these oxidation reactions, cells start stress responses. A lot of the key molecules, e.g reactive oxygen species molecules (ROS), would be produced during oxidative stress and they play an extremely important role. The analysis and detection of these key molecules can not only help to understand the important roles of these molecules in the oxidative stress process, but also can have a deeper understanding of the occurrence and development of diseases. In this review, we focused on summarizing the surface-enhanced Raman spectroscopic techniques that realize the analyses and detections of the key molecules of oxidative stress in cells. Starting from the designed strategies of SERS methods, we classified and summarized the existing methods, enumerated a number of research work of Chinese scientists, and displayed the outlook for this field.

Key words

oxidative stress / intracellular detection / SERS / SERS tag / ROS

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YUE Jing, SHEN Yanting, WANG Jiaqi, XU Weiqing, XU Shuping. SERS detection methods for several key molecules in the oxidative stress process of cells. Chinese Journal of Light Scattering. 2019, 31(4): 317-325 https://doi.org/10.13883/j.issn1004-5929.201904003

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