Solid-state nanopore has emerged as a powerful single-molecule method due to its label-free and high-throughptu capabilities, and high temporal and spatial resolution. It has been widely used in the detection of single molecules, including DNA, RNA, proteins, metal ions and others. This review mainly focuses on the integrated system of plasmon resonance scattering spectroscopy and solid-state nanopores, summarizes the research progress in this field, briefly discusses the princeples, fabrications and applications of these electro-optical nanopore, and further prospects the Raman scattering spectroscopy in solid-state nanopores.