CAO Lu, ZHU Jiasen, GUAN Yanyan, ZHANG Weihong, GONG Li, XIE Fangyan, ZHOU Haibo, LAI Zhihui, CHEN Jian
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Raman spectroscopy has been widely used in pharmaceutical analysis due to its remarkable characteristics such as avoiding the interference of water in samples,simplicity of sample pretreatment,rapid nondestructive analysis,and greatly enhancing the sensitivity of detection by Surface Enhanced Raman Spectroscopy.The purpose of this paper is to summarize the specific research examples of Raman spectroscopy in drug identification,drug quantitative analysis,drug crystal analysis,quality control process monitoring of drug production,pharmacokinetics and so on in the past ten years,and to make a comprehensive review of the research and application of Raman spectroscopy in the field of drug analysis,so as to provide necessary reference for future research in this field.